When Vision Is At Risk,Guesswork Isn't AnOption

Detect Eye Infections Accurately with:

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EyePathogen 0Pathogen 1Pathogen 2Pathogen 3Pathogen 4

Ocular Infections in India: The Diagnostic Gap

High Burden

High Burden

  • ~1.3 million Indians suffer from bilateral corneal blindness¹
  • Ocular infections remain a leading preventable cause of corneal blindness²
Diverse Pathogens

Diverse Pathogens

  • Bacterial, fungal, viral, and parasitic etiologies
  • Mixed and rare pathogens frequently missed
Low Diagnostic Yield

Low Diagnostic Yield

  • Low pathogen load and limited sample volumes
  • Viral and fastidious organisms often undetected
Diagnostic Limitations

Diagnostic Limitations

  • Empirical therapy before testing is common
  • Limited sample volume reduces detection sensitivity

1. Parihar, M. G. J. (2024). Corneal blindness eye banking: Current status & challenges ahead. Annals of the National Academy of Medical Sciences (India), 60, 241-243.

2. Vashist, P., Gupta, N., Tandon, R., Gupta, S., & Sreenivas, V. (2013). Burden of corneal blindness in India. Indian Journal of Community Medicine, 38(4), 198.

OPHTHAL-NGS Logo

The Only Comprehensive Test for Eye Infections

Ophthal-NGS is a next-generation sequencing (NGS) based diagnostic test designed for comprehensive detection of ocular pathogens. By analysing directly from ocular samples, Ophthal-NGS delivers an unbiased, culture-free view of infectious agents, enabling accurate diagnosis even in complex cases.

Workflow Diagram

Broad-Spectrum Pathogen Detection

From a single sample, Ophthal-NGS can simultaneously detect:

Pan-Bacteria
Pan-Bacteria
Viruses (Neuropathic viruses)
Viruses (Neuropathic viruses)
Major Antimicrobial Resistance Genes (ARGs)
Major Antimicrobial Resistance Genes (ARGs)
Pan-Fungi
Pan-Fungi
Commonly Implicated Ocular Pathogens
Commonly Implicated Ocular Pathogens
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Scan for complete list of pathogens detected

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Sample Requirements

Ophthal-NGS is optimised for low sample volumes, making it suitable even for delicate or critical cases.

Types of Samples We Accept

  • Aspirated pus (500 µl)
  • Aqueous humour (≥100 µl)
  • Vitreous humour (500 µl – 2 ml)
  • Corneal button
  • Ocular tissue

Sample Notes

  • Sterile container or sterile syringe required
  • Swabs are not accepted for extra-ocular sample type

How Ophthal-NGS Works

Workflow Diagram

Designed to integrate seamlessly into existing clinical workflows.

Clinical Applications

Ophthal-NGS supports diagnosis across a wide spectrum of ocular infections, including:

Infectious KeratitisInfectious Keratitis
UveitisUveitis
EndophthalmitisEndophthalmitis
PanophthalmitisPanophthalmitis
RetinitisRetinitis

Particularly valuable in refractory, atypical, or culture-negative cases.

What Makes Ophthal-NGS the Best

Parameter

Viral detection
Bacterial detection
Co-infection detection
Comprehensive profiling
Specificity
Results
Supports antibiotic stewardship

Culture

Limited
Yes
Limited
No
Low
Take 3 to 7 days
Moderate
Ophthal NGS
Yes
Yes
Yes
Yes
Very high (>99%)
Within ~24 hours
High

Evidence-Based Diagnostics for Doctors

Clinical Impact

Clinical Impact

  • Culture-free infection detection
  • Bacteria, fungi, viruses detection in one single test
  • Co-infection & ARG detection
  • Faster treatment decisions (~24 hours)
Key Advantages

Key Advantages

  • Enables detection in low-volume samples
  • Reliable co-infection insights
  • Actionable AMR guidance
  • Reduced culture dependence
Strategic Advantage

Strategic Advantage

  • Differentiates your centre with advanced genomics-based diagnostics
  • Supports complex & referral-level cases
  • Enable antimicrobial stewardship

From Uncertainty to Clarity, In One Test

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Complete infection insight from a single sample

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Clear answers even when cultures fail

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Faster, evidence-based treatment decisions

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Designed for complex, sight-critical cases